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Confidently rule in or rule out1 with Delve Detect. Identify infectious bacteria, viruses, fungi, and parasites using a single test.

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Add mNGS to your infectious disease toolkit

Traditional, targeted tests offer a frustrating guessing game with too many tests and too few answers. Metagenomic sequencing (mNGS) ends the cycle.

Delve Detect analyzes all nucleic acids in a sample – RNA and DNA – directly from the site of infection to accurately identify the pathogens present and deliver more comprehensive microbial analysis than conventional testing.

  • Detect over 68,000 pathogens through Delve Decide, our proprietary, curated pathogen database, bioinformatics pipeline, and clinical interpretation software
  • Free, easy-to-use kit enables overnight shipping of CSF samples at room temperature
  • Delivers results in 48 hours after a sample is received

Real world evidence highlights clinical impact of mNGS (CSF)

From the largest cohort analyzed-to-date involving more than 4,800 patients, mNGS (CSF) provides more comprehensive microbial analysis than other infectious disease tests.1

437

pathogens identified

17.8%

positivity rate*

22%

greater diagnostic yield

*14.4% positivity when samples with multiple taxa are removed.

Prospective, multicenter clinical trial demonstrates the clinical actionability of mNGS2

Year-long, multi-center, prospective enrollment with over 200 patients from hospitals across the United States demonstrates actionability of mNGS results.2

54%

of clinical diagnoses made by mNGS alone resulted in treatment change

22.4%

of infections missed by standard microbiological testing

55%

of diagnoses were made using mNGS – alone or in conjunction with other testing

Learn more about mNGS
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Expert support every step of the way

Delve Bio was founded by experts in infectious disease – and they’re ready to support your team. Delve’s Clinical Microbial Sequencing Board provides every Delve customer with access to Delve’s expert medical affairs team. From patient identification to clinical consultation, Delve Bio becomes an extension of your team, helping you deliver accurate, complete answers for patients.

Talk to our medical team
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A diagnosis makes all the difference3

A 14-year-old with severe combined immunodeficiency developed an infection that progressed from a headache to seizures requiring a medically induced coma.

After multiple hospitalizations, more than 40 diagnostic tests and a brain biopsy, there was still no clear answer on what was wrong.

Finally, a mNGS CSF test was ordered.

Within hours, mNGS identified a bacterial pathogen (Leptospira), despite previous negative microbiological testing. 48 hours after treatment started, the patient was conscious. He was home and back to normal within a month – thanks to the accurate diagnosis mNGS provided.

Learn more about metagenomics

NEJM-min

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis.

THE NEW ENGLAND JOURNAL OF MEDICINE 2019

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References and Citations
  1. Benoit, P., et al. Nature Medicine, in press.
  2. Wilson MR, Sample HA, Zorn KC, et al. Clinical metagenomic sequencing for diagnosis of meningitis and encephalitis.N Engl J Med 2019; 380:2327–40.
  3. Wilson MR, et al. Actionable Diagnosis of Neuroleptospirosis by Next-Generation Sequencing. N Engl J Med 2014;370:2408-2417